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    输尿管软镜取石术与经皮肾镜取石术治疗2~3 cm肾结石的有效性和安全性分析

    Analysis of the efficacy and safety of flexible ureteroscopy lithotripsy and percutaneous nephrolithotomy in the treatment of kidney stone with a diameter of 2 to 3 cm

      摘要
    • 摘要:
      目的 比较经皮肾镜和输尿管软镜取石术在治疗2~3 cm肾结石中的作用。
      方法 回顾性分析50例2~3 cm肾结石病人的病例资料，行经皮肾镜取石术（percutaneous nephrolithotomy，PCNL）的病人设为PCNL组，行输尿管软镜取石术（flexible ureteroscopy lithotripsy，FURL）的病人设为FURL组，每组25例。分析2组结石清除率手术时间输血率血红蛋白下降量术后住院时间等。
      结果 FURL组和PCNL组的结石清除率分别为72.00%和80.00%，差异无统计学意义（P>0.05）。PCNL组的手术时间明显短于FURL组（P < 0.01），PCNL组的血红蛋白下降量和术后住院时间明显大于FURL组（P < 0.01），2组病人的结石清除率差异无统计学意义（P>0.05）。2组病人的输血率、术后发生尿路感染率和二期手术或行ESWL率差异均无统计学意义（P>0.05）
      结论 FURL和PCNL均是治疗2~3 cm肾结石的有效方法，与PCNL相比，FURL失血更少，恢复时间短。

       

      Abstract:
      Objective To compare the clinical effects between percutaneous nephrolithotomy (PCNL) and flexible ureteroscopy lithotripsy (FURL) in the treatment of kidney stone with a diameter of 2 to 3 cm.
      Methods The clinical data of 50 patients with kidney stone were retrospectively analyzed.Twenty-five cases treated with PCNL and 25 cases treated with FURL were divided into the PCNL group and FURL group, respectively.The stone-free rate, operating time, blood transfusion rate, hemoglobin drop and postoperative hospitalization time were compared between two groups.
      Results The stone clearance rates in the FURL group and PCNL group were 72.00% and 80.00%, respectively, and the difference of which was not statistically significant (P>0.05).The operation time in PCNL group was shorter than that in FURL group (P < 0.01), and the hemoglobin drop and postoperative hospitalization time in PCNL group were greater than those in FURL group (P < 0.01).There was no statistical significances in the blood transfusion rate, postoperative urinary tract infection rate, and secondary surgery or ESWL rate between two groups (P>0.05).
      Conclusion Both FURL and PCNL are effective methods for treating kidney stones with a diameter of 2 to 3 cm, but FURL has less blood loss and shorter recovery time compared with PCNL.

       

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