Abstract: Objective: To investigate the compliance of insulin injection and its influence factors in elderly patients with type 2 diabetes for taking corresponding measures to improve the compliance of insulin injection.Methods: Two hundred and ten elderly patients with type 2 diabetes were investigated by questionnaire survey to know the compliance of insulin injection,and analyze its influence factors.Results: The compliance of insulin injection in 129 cases and 81 cases were good and poor,respectively.The poor compliance of insulin injection included non-consistent injecting everyday(21.9%),non-complying with the doctor's advice(32.4%),incorrect injection time(39.0%),incorrect injection time(34.3%),incorrect injection position,incorrect rotation principle(42.4%) and non-eating on time(39.0%).The age,the degree of cognition,culture,income,family support and disease knowledge education were the compliance factors of insulin injection in elderly patients with type 2 diabetes(P<0.05).Conclusions: Many factors can affect the compliance of insulin injection in elderly patients with type 2 diabetes.Implementing health education,providing social support and improving the correct knowledge of insulin can improve the compliance of insulin injection.