Abstract: Objective:To summary the genotyping, clinical manifestations, diagnosis and clinical treatment of eosinophil gastroenteritis(EG).Methods:One EG child with recurrent gastrointestinal symptoms, excluding parasitic infections, blood system cancer and other diseases, was dignosed by examination, who was treated with anti-allergic drugs, leukotriene inhibitor and corticosteroid.The time of clinical symptoms remission and disappear, and laboratory index recovery were observed.Results:The recurrent vomiting, abdominal pain, diarrhea and other gastrointestinal symptoms, even dysphagia, intestinal obstruction and intestinal perforation, were the clinical features of EG.The laboratory test showed that eosinophilia granulocyte of peripheral blood increased.The rough mucosal congestion and edema, and point flake erythema or erosion were found by endoscopic examination.Fifteen to twenty eosinophils per high power field of the lesion were identified by pathology examination.The laboratory parameters returned to normal level, and clinical symptoms improved or disappeared after treatment.Conclusions:EG is a gastrointestinal allergic benign disease, the effect of which treated with corticosteroid is effective.