柳立新, 杨冬梅, 刘俊, 刘建军. 安徽省县级医院药品不良反应1944例原因分析[J]. 蚌埠医科大学学报, 2015, 39(7): 943-946. DOI: 10.13898/j.cnki.issn.1000-2200.2015.07.039
    引用本文: 柳立新, 杨冬梅, 刘俊, 刘建军. 安徽省县级医院药品不良反应1944例原因分析[J]. 蚌埠医科大学学报, 2015, 39(7): 943-946. DOI: 10.13898/j.cnki.issn.1000-2200.2015.07.039
    LIU Li-xin, YANG Dong-mei, LIU Jun, LIU Jian-jun. Retrospective analysis of 1 944 adverse drug reaction case reports of county hospitals in Anhui province[J]. Journal of Bengbu Medical University, 2015, 39(7): 943-946. DOI: 10.13898/j.cnki.issn.1000-2200.2015.07.039
    Citation: LIU Li-xin, YANG Dong-mei, LIU Jun, LIU Jian-jun. Retrospective analysis of 1 944 adverse drug reaction case reports of county hospitals in Anhui province[J]. Journal of Bengbu Medical University, 2015, 39(7): 943-946. DOI: 10.13898/j.cnki.issn.1000-2200.2015.07.039

    安徽省县级医院药品不良反应1944例原因分析

    Retrospective analysis of 1 944 adverse drug reaction case reports of county hospitals in Anhui province

    • 摘要: 目的:分析安徽省县级医院药品不良反应(ADR)报告特点及规律,促进临床合理用药。方法:对9家县级医院2012和2013年度上报的ADR报告进行分类和分析。结果:1 944例ADR报告中,给药途径主要为静脉注射(73.8%);累及器官和临床表现主要为皮肤及附件损害(30.3%);药物品种主要为抗菌药物(38.7%);2年度9家县级医院报告ADR的给药途径、累及器官或系统、引起ADR药物品种和不同医院报告病例数构成差异均有统计学意义(P结论:ADR的发生与给药方式、药品种类有关,ADR监测和报告制度在县级医院执行差异较大。

       

      Abstract: Objective:To analyze the characteristics and regularities of the adverse drug reactions(ADR) in county hospitals of Anhui province,for improving the rational use of drug in clinic.Methods:A total of 1 944 cases of ADR reports collected from nine county level hospitals of Anhui province from 2012 to 2013 were statistically classified and analyzed.Results:The main cause of ADR was originated from intravenous administration(73.8%);damaging the skin and its appendages was the main lesion in ADR cases(30.3%);about 38.7% of ADR cases were mainly caused by using antimicrobial drugs;the difference of the drug delivery route,organs or systems involved,type of drugs and the number of reported cases in different hospital has statistical significance(PConclusions:The occurrence of ADR related to the routs of drug delivery and the type of drug,ADR monitoring and reporting system in county hospital execute differently.

       

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