Abstract: Objective:To observe the clinical effects of Shenlingbaizhu powder combined with Gualou Xiebai Banxia Decoction in the treatment of thoracic obstruction.Methods:Forty patients with phlegm closed resistance type thoracic obstruction were randomly divided into the control group and observation group(20 cases each group).The control group were treated with oxygen,100 mg of Aspirin Enteric-coated tablets 1 time daily for anti-platelet aggregation,20 mg of isosorbide mononitrate tablet twice a day for expanding and improving myocardial ischemia and 10 mg of simvastatin before sleep every night for stabling the lipid plaque.The observation were additionally treated with Shenlingbaizhu powder combined with Gualou Xiebai Banxia Decoction based on the control group treatment.The symptom score,electrocardiogram improvement rate,clinical curative effects andblood lipid between two groups were analyzed.Results:Except the lassitude score in control group,the symptoms scores in two groups after treatment were lower than those in before treatment(P<0.05 to P<0.01).The treatment effects,except the chest pain score,in observation group were better than those in control group(P<0.05 to P<0.01).Compared with those before treatment,the levels of low density lipoprotein cholesterol,triglyceride and total cholesterol in the two observation groups after treatment are significantly decreased(P<0.01),and the level of high density lipoprotein cholesterol isdid not significantly elevatedincrease(P>0.05).The levels of low density lipoprotein cholesterol and total cholesterol in the observation group are were lower than those in the control group(P<0.01 and P<0.05),and the level of high density lipoprotein cholesterol of the in observation group iswas higher than that of the control group after treatment(P<0.01).Conclusions:The clinical effects of Shenlingbaizhu powder combined with Gualou Xiebai Banxia Decoction in the treatment of thoracic obstruction are good,which is worthy of clinical promotion.