Abstract: Objective:To investigate the use of mobile phone among the college students,and explore the relationship between the mobile phone dependence and compulsive tendency.Methods:Two hundred and ninety-one female students of nursing profession from a Anhui college were anonymously investigated using the cluster sampling,self-rating questionnaire for adolescent problematic mobile phone use and Yale-Brown obsessive compulsive scale,the general condition and mobile phone use were analyzed.Results:The total average score of mobile phone dependence was(24.45±5.807),the high scores in 80 cases were found.The differences of the mobile dependence between different daily usage time and years of usage students were statistical significance(P<0.01 and P<0.05).The differences of the mobile dependence between different scores ranking and make-up examination subjects students were statistical significance(P<0.01).The phone dependence total score was positively correlation with compulsive symptom score(P<0.01).A linear stepwise regression analysis indicated that the total score of mobile dependence can predict the total score of compulsive symptom(β=0.202,P<0.01).Conclusions:The college student with more dependence of mobile phone is prone to compulsive tendency.Effective reducing the use time of mobile phone can help prevent the dependence of mobile phone and compulsive tendency.