Abstract: Objective:To discuss of the influence of empathy technique intervention on the life quality,psychological status and subjective well-being of patients with senile osteoporosis.Methods:One hundred and seventy patients with senile osteoporosis were randomly divided into control group and observation group(n=85 in each group).The patients in the control group were given only the routine nursing of senile osteoporosis,and the observation groups received psychological comfort,encouragement,symptomatic treatment and empathy technique in addition to the routine nursing.The quality of life,psychological status and subjective well-being of the two groups were observed.Results:After intervention,the score of life quality index rating scale of the observation group was significantly higher than that of the control group(P<0.05);the scores of Self-rating Anxiety Scale and Self-rating Depression Scale of the observation group were significantly lower than those of the control group(P<0.01);and the score of subjective well-being of the observation group was significantly higher than that of control group(P<0.01).Conclusions:Empathy technique can effectively improve the life quality of the elderly with osteoporosis,reduce their symptoms of anxiety and depression,and improve their subjective well-being.