良性前列腺增生与原发性高血压的关系

    Relationship between benign prostatic hyperplasia and primary hypertension

    • 摘要: 目的:探讨良性前列腺增生(BPH)与原发性高血压之间的关系。方法:将100例BPH患者分为2组,其中BPH合并原发性高血压组(A组)45例,单纯 BPH组(B组)55例。A组内再根据收缩压、舒张压、高血压病程的长短分小组。对A、B组患者的发病年龄、国际前列腺症状评分(IPSS)、残余尿量、前列腺体积(PV)、血清前列腺特异性抗原、尿潴留次数等指标进行统计学分析。结果:A组患者年龄、IPSS评分、PV和尿潴留次数均大于B组(P<0.05~P<0.01)。A组中收缩压>160 mmHg组的年龄与B组差异有统计学意义(P<0.01);舒张压90~110 mmHg及舒张压>110 mmHg组的PV和尿潴留次数均大于B组(P<0.05~P<0.01);高血压病程>20年组的发病年龄、IPSS评分和尿潴留次数均大于高血压病程<10年组与病程10~20年组(P<0.05~P<0.01)。结论:高血压可能会对BPH的发生及临床进展产生影响,及早地控制和改善高血压,有利于减轻BPH相关症状。

       

      Abstract: Objective: To investigate the relationship between benign prostatic hyperplasia(BPH) and primary hypertension. Methods: One hundred BPH patients were divided into the BPH complicated with hypertension(group A, 45 cases), and hypertension group(group B, 55 cases). The group A were subdivided into team according to the systolic and diastolic pressure, and the course of hypertension. The age, IPSS, PV, PSA and urinary retention times between two groups were analyzed by statistical method. Results: The age, IPSS, PV and urinary retention times in group A were significantly higher than those in group B(P<0.05 to P<0.01). The difference of age in the patients with systolic pressure more than 160 mmHg was statistically significant(P<0.01). The urinary retention times and PV in group A with systolic pressure from 90 to 110 mmHg and diastolic pressure more than 110 mmHg were higher those in group B(P<0.05 to P<0.01). The age, IPSS and urinary retention times in the patients with hypertension course more than 20 years were more than those in the patients with hypertension course less than 10 years and from 10 years to 20 years(P<0.05 to P<0.01). Conclusions: Hypertension may affect the occurrence and clinical progression of BPH. Early controlling and improving high blood pressure can be conducive to relieving the symptoms.

       

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