Abstract: Objective:To explore the protective effects of the nano carbon technology on the parathyroid during the operation of thyroid cancer.Methods:Fifty patients with thyroid carcinoma were randomly divided into the control group and nano carbon group.Parathyroid mistakenly cut in the lymph adipose tissue, postoperative blood calcium and parathyroid hormone levelss, and the incidence of clinical symptoms of postoperative parathyroid injury between two groups were compared.Results:The parathyroid gland in black dye organization in nano carbon group was not found.The incidence of postoperative clinical symptoms of parathyroid damage in nano carbon group was less than that in control group(P<0.05 to P<0.01).The levels of blood calcium and parathyroid hormone in nano carbon group were higher than those in control group at d 1, d 3 and 3 months of operation(P<0.05 to P<0.01).Conclusions:The lymphatic drainage way of thyroid and parathyroid is different.The nano carbon tracer in thyroid lymphatic system can well identify parathyroid gland, reduce the damage probability of parathyroid gland during the thyroid cancer lymph node cleaning.