Abstract: Objective:To explore the correlation of the serum total cholesterol level with mortality in elderly male patients with coronary heart disease.Methods:Two hundred and eight elderly male patients with coronary heart disease were divided into the group A(serum total cholesterol <4.16 mmol/L), group B(4.16 mmol/L≤serum total cholesterol <4.68 mmol/L), group C(4.68 mmol/L≤serum total cholesterol <5.20 mmol/L) and group D(serum total cholesterol >5.20 mmol/L) according to the serum total cholesterol levels.The serum triglyceride level, physical examination, age, body mass index and mortality in all patients were analyzed.Results:The differences of the serum total cholesterol levels between four groups were statistically significant(P<0.01).The mortalities in group A and D were higher than that in group B, and the mortality in group D was higher than that in group C(P<0.05).The differences of the mortalities in group A & group D and group B & group C were not statistically significant(P>0.05).The differences of age, body mass index and triglyceride level between four groups were not statistically significant(P>0.05).The mortality in elderly male coronary heart disease patients with serum total cholesterol levels <4.16 mmol/L or >5.20 mmol/L increased.Conclusions:The serum total cholesterol level in elderly male patients with coronary heart disease is closely correlated to the mortality.The high or low serum total cholesterol levels are the risk factors of the death of the elderly male patients with coronary heart disease.