Abstract: Objective:To investigate the surgical method and clinical effects of the free dorsal interosseous artery perforator flap on repairing the middle and small area skin defect of hand.Methods:The free dorsal interosseous artery perforator flap was obstained,the area of which was 2.0 cm×3.6 cm to 4.0 cm×8.0 cm.The microvascular anastomosis was implemented by end-to-end or end-to-side,the donor position was directly sutured.Results:All 19 flaps survived.The patients were followed up for 6 to 12 months.The texture of flap and hand function were good,only the linear scar was found in donor position.Conclusions:The dorsal interosseous artery perforator flap has stably anatomical structure,fine texture and suitable thickness,which is suitable for the repair of the middle and small area skin defect of hand.