宫颈阴道分泌物胎儿纤维连接蛋白检测在孕足月分娩中的预测作用

韩春薇; 万敏

doi:10.13898/j.cnki.issn.1000-2200.2016.07.022

宫颈阴道分泌物胎儿纤维连接蛋白检测在孕足月分娩中的预测作用

韩春薇,
万敏

The predictive effect of the detection of cervicovaginal secretion fetal fibronectin in term pregnancy

摘要

摘要: 目的：研究宫颈阴道分泌物胎儿纤维连接蛋白（FFN）检测结果对分娩的临床预测作用。方法：选择247例孕妇，孕37～41⁺⁶周，分为FFN阳性组和阴性组，对比2组孕妇的分娩方式；并在2组中遴选阴道分娩的产妇，对比其分娩时间，评价FFN在分娩中的预测价值。结果：宫颈阴道分泌物FFN检测阳性的孕妇其阴道分娩率为70.83%，剖宫产率为29.17%；而宫颈阴道分泌物FFN检测阴性的孕妇阴道分娩率为57.48%，剖宫产率为42.52%，差异有统计学意义（P<0.05）。阴道分娩的FFN阳性组孕妇分娩时间明显少于FFN阴性组（P<0.01）。阴道分娩的FFN阳性组孕妇7 d内分娩率为90.59%，阴性组为67.12%，差异有统计学意义（P<0.01）。结论：宫颈阴道分泌物FFN检测在分娩预测中具有临床指导意义。

Abstract: Objective: To investigate the clinical predictive effect of the ervicovaginal secretion fetal fibronectin(FFN) in term pregnancy.Methods: Two hundred and forty-seven pregnant women with 37 to 41⁺⁶ pregnancy weeks were divided into the positive and negative FFN group.The delivery methods between two groups were compared.The puerperas with vaginal delivery were selected,the delivery time of which was analyzed for evaluating the value of FFN in intrapartum.Results: The vaginal delivery and cesarean section rates in the pregnant women with the positive expression of cervicovaginal secretion FFN were 70.83% and 29.17%,respectively,while the vaginal delivery and cesarean section rates in the pregnant women with the negative expression of cervicovaginal secretion FFN were 57.48% and 42.52%,respectively,the difference between two groups was statistically significant(P<0.05).The vaginal delivery time in pregnant women with positive FFN was significantly less than that in pregnant women with negative FFN(P<0.01).The 7 d-delivery rates in pregnant women with positive FFN and negative FFN were 90.59% and 67.12%,respectively,the difference of which was statistically significant(P<0.01).Conclusions: The detection of cervicovaginal secretion FFN in term pregnancy has clinical significance.

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