Abstract: Objective: To investigate the clinical effects of the predictive nursing on preventing the pressure ulcers in ICU patients.Methods: Sixty-eight severe patients from April 2011 to December 2012 were set as the control group,and 68 severe patients from January 2013 to August 2014 were set as the intervention group.The control group and intervention group were nursed with routine way and predictive pressure ulcer nursing,respectively.Results: The incidence rate of pressure ulcer in intervention group(19.12%) was significantly lower than that in control group(51.47%)(P<0.01).The severity of pressure ulcer in intervention group was lighter than that in control group(P<0.05).Conclusions: The application of the predictive nursing can effectively decrease the incidence rate and severity of pressure ulcers.