Abstract: Objective:To analyze the perinatal complications and its treatment in late preterm infants with small for gestational age(SAG).Methods:The clinical data of 349 late preterm infants,which included 187 SGA infants and 162 appropriate for gestational age(AGA) infants,were investigated.The perinatal condition,general condition after birth,complications,treatment outcome and prognosis between two groups were compared.Results:The incidences of perinatal mother pregnancy-induced hypertension syndrome,infection during pregnancy,umbilical cord abnormality and fetal distress in SGA group were 43.32%,11.23%,26.20% and 18.72%,respectively,which was higher than that in AGA group(P < 0.05 to P < 0.01).The gestational age and 1 min Apgar score in SGA group were significantly lower than that in AGA group(P<0.01),and the hospitalization time in SGA group were significantly longer than that in AGA group(P<0.01).The incidences of respiratory distress syndrome(RDS),infection,hyperbilirubinemia,and intravenous nutrition application in SGA group were 45.99%,61.50%,32.09%,and 85.56%,respectively,whose were higher than those in AGA group(P < 0.05 to P < 0.01).The recovery rate of complication in SGA group(56.14%) was lower than that in AGA group(70.54%)(P<0.05).The difference of the developmental situation between two groups was not statistically significant(P>0.05).Conclusions:Compared with the AGA infants,the incidence rate of complication and cure rate in SAG infants were higher and lower,respectively.The mother pregnancy-induced hypertension syndrome,infection during pregnancy,umbilical cord abnormality and fetal distress are the main reasons of late preterm infants with SGA.The clinicians should pay high attentions to the characteristics of SGA,and early intervene the risk factors.