Abstract:
Objective:To investigate the effects of different glucose tolerance status during pregnancy on pregnancy outcome.
Methods:One thousand seven hundred and one singleton pregnant women were divided into the gestational impaired glucose tolerance group(GIGT group),gestational diabetes mellitus group(GDM group) and euglycemia group(control group) according to the blood sugar status in pregnancy.The data of patients were retrospectively analyzed.
Results:The maternal age in GIGT group and GDM group were significantly higher than that in control group(
P<0.01).The pre-pregnancy weight,over weight and obesity rates in GDM group were higher than those in control group(
P<0.01 and
P<0.05).The pre-pregnancy weight in GIGT group was lower than that in GDM group(
P<0.01),but the differences of the prenatal weight and BMI between three groups were not statistically significant(
P>0.05).The incidence rates of the premature rupture of membrane and polyhydramnios in GIGT and GDM groups were higher than those in control group(
P<0.05),the incidence rates of macrosomia and cesarean in GDM group were higher than those in control group(
P<0.05),and the incidence rate of cesarean in GIGT group was lower than that in GDM group(
P<0.05).The differences of the incidence rates of postpartum hemorrhage between three groups were statistically significant(
P<0.01).The differences of the incidence rates of hypertensive disorders in pregnancy,premature birth and hypothyroidism between three groups were not statistically significant(
P>0.05).
Conclusions:Both GIGT and GDM can harm the health of mothers and children,which should be emphasized.The proper pregnancy and controlling pre-pregnancy weight can reduce the incidences of GDM and GIGT.