Abstract: Objective:To evaluate the effects of the review tool intervention on the reasonable medication in community senile patients with chronic diseases based on Beers standard.Methods:Two hundred community senile patients with chronic diseases were randomly selected,and divided into the control group(103 cases) and intervention group(97 cases).The control group were instructed with routine medication,and the intervention group were instructed with the review tool intervention of the reasonable medication based on the Beers standard.The medication between two groups was compared.Results:The differences of the benefit of medication and indicators of life quality before intervention between two groups were not statistically significant(P>0.05).After intervention,the adverse reactions,amount and cost of medication in intervention group were significantly less than those in control group(P<0.01),but the compliance of medication in intervention group was significantly better than that in control group(P<0.01).The difference of the super indications medication between two groups was not statistically significant(P>0.05).The indicators of life quality in intervention group was better than that in control group(P<0.05 to P<0.01).Conclusions:The review tool intervention of the reasonable medication in community senile patients with chronic diseases based on Beers standard is safe and effective,which can lighten the financial burden and improve the quality of life and health of patients,and is worth popularizing.