Abstract: Objective:To compare the effects between hemodialysis and peritoneal dialysis on calcium and phosphorus metabolism in patients with uremia.Methods:The clinical data of 52 patients with uremia were retrospectively analyzed.Twenty-eight cases treated with peritoneal dialysis and 24 cases treated with hemodialysis were divided into the peritoneal dialysis group and hemodialysis group,respectively.The levels of the parathyroid hormone,serum phosphorus and calcium in two groups were measured at treatment,and 3 and 6 months after treatment.The incidence rate of abnormal situation between two groups was compared.Results:The levels of serum phosphorus in peritoneal dialysis group at treatment and 6 months after treatment were lower than that in hemodialysis group(P<0.05).The level of parathyroid hormone in peritoneal dialysis group at treatment was significantly lower than that in hemodialysis group(P<0.05).The incidence rate of high phosphorus in peritoneal dialysis group was significantly lower than that in hemodialysis group(P<0.05).The differences of the incidence rate of low phosphorus,high and low calcium and parathyroid hormone between two groups were not statistically significant(P>0.05).Conclusions:The peritoneal dialysis can effectively protect the residual renal function and control the calcium and phosphorus metabolism,which is worthy of clinical application.