Abstract: Objective:To investigate the physical exercise of medical college students,and analyze the effects of physical exercise on the self-confidence of students.Methods:One thousand and eight from the "Department of Clinical Medicine and Nursing" of a medical college were selected using stratified cluster sampling.The students were investigated using self-programming "Physical Exercise Questionnaire" and "College Student Self-confidence Questionnaire" in group way.Results:The average score of self-confidence of medical students was(240.02±35.55) points.In physical exercise,a small amount of exercise was taken by a majority of students(74.5%).The total score of self-confidence and each dimension score in the students taking moderate and large intensity exercise were higher than those in the students taking small intensity exercise(P<0.01).Multiple linear regression results showed that the self-confidence in male,lower grade,and high maternal educational level and large intensity exercise students were higher(P <0.05 to P <0.01).The self-confidence in "Medical Imaging Department" was higher than that in "Preventive Medicine Department"(P<0.05).Conclusions:The self-confidence levels in the students taking moderate and large intensity exercise are higher than that in the students taking small intensity exercise.The self-confidence levels in male,lower grade,high maternal educational level and large intensity exercise medical students are more high.