Abstract: Objective:To investigate the efficacy of the percutaneous minimally invasive pedicle screw rod internal fixation in the treatment of thoracolumbar fractures.Methods:Ninety-eight patients with thoracolumbar fractures were divided into the observation group and control group,were treated with percutaneous minimally invasive and traditional opening pedicle screw rod internal fixation,respectively.The curative effects between two groups were compared.Results:The operation time,incision length,bleeding volume,postoperative drainage volume and postoperative visual analogue scale 1 day score in observation group were significantly less than those in control group(P<0.01).The differences of the percentage of vertebral anterior height,postoperative 1 week and 1 year sagittal plane Cobb angle,and Oswestry disability index between two groups were not statistically significant(P>0.05).Conclusions:The percutaneous minimally invasive pedicle screw rod internal fixation in the treatment of thoracolumbar fractures is effective,which is less trauma,quick recovery and light pain,and worthy of clinical application