Abstract: Objective:To investigate the nursing effects of humane care nursing mode on glioma patients.Methods:Sixty-two patients with glioma were randomly divided into the control group and observation group(31 cases each group).The control group and observation group were nursed with routine care and humane care nursing mode,respectively.The hope index,mentality state and quality of life in two groups were evaluated after intervention.Results:Compared with before intervention,the three dimension scores of hope level scale in two groups significantly increased after intervention(P<0.01),and the increasing degree of which in observation group was higher than that in control group(P<0.01).Compared with before intervention,the scores of self rating anxiety scale,self rating depression scale and dysfunctional attitude questionnaire in two groups significantly decreased after intervention(P<0.01),and the decreasing degree of which in observation group was more obvious than that in control group(P<0.01).After intervention,the scores of psychological and emotional state,physical function and daily life in observation group were significantly higher than those in control group(P<0.05 to P<0.01),but the difference of the score of social activity between two groups was not statistically significant(P>0.05).Conclusions:The humane care nursing mode can significantly improve the hope level scale index,anxiety,depression and quality of life,which is a good way to improve the quality of care in glioma patients.