ObjectiveTo explore the influence of minimally invasive percutaneous tracheotomy in the treatment of laryngeal cancer on clinical effect and stress response of patients.

MethodsOne hundred and twenty patients with laryngeal cancer were randomly divided into the control group(60 cases) and observation group(60 cases).The control group was treated with conventional tracheotomy, and the observation group was treated minimally invasive percutaneous tracheotomy.The level of blood rheology, operation, stress response index and postoperative complications between two groups were compared.

ResultsAt T₂, T₃, T₄ and T5, the SBP, DBP, HR and breathing rate in two groups significantly increased compared with at T₁, and the differences of those among different time-points were statistically significant(P < 0.01).The SBP, DBP, HR and breathing rate in observation group at T₂, T₃, T₄ and T₅ were significantly lower than those in control group(P < 0.01).The operation time, incision length, intraoperative blood loss and wound healing time in observation group were significantly lower than those in control group(P < 0.01).The levels of blood glucose, cortisol, IL-6 and and CRP significantly increased in two groups at T'₂, T'₃ and T'₄, and the differences of those among different time-point were statistically significant(P < 0.05 to P < 0.01).The levels of blood glucose, cortisol, IL-6 and and CRP in observation group were significantly lower than those in control group(P < 0.05 to P < 0.01).The incidence rate of postoperative complications and skin dent rate in observation group were significantly lower than that in control group(P < 0.01).

ConclusionsThe minimally invasive percutaneous tracheotomy in treating laryngeal cancer has good effect and simple operation, which can significantly decrease intraoperative blood loss, operation time, stress response indicators and postoperative complications, and avoid postoperative skin dents.