复方血栓通胶囊联合胰激肽原酶肠溶片治疗视网膜病变的临床效果

    Clinical effect of compound Xueshuantong capsule combined with pancreatic kininogenase enteric-coated tablets in the treatment of retinopathy

    • 摘要:
      目的探讨复方血栓通胶囊联合胰激肽原酶肠溶片治疗视网膜病变的临床效果。
      方法选取确诊为非增殖期视网膜病变病人60例,随机分为对照组与观察组,各30例。对照组病人仅给予胰激肽原酶肠溶片治疗,观察组病人联合使用复方血栓通胶囊与胰激肽原酶肠溶片进行治疗,比较2组病人疗效和血液流变学、血流动力学指标。
      结果观察组病人的总有效率为96.67%,略高于对照组的80.00%,但2组差异无统计学意义(P > 0.05)。治疗后2组病人血细胞比容、红细胞聚集指数、全血高切黏度均较治疗前明显改善(P < 0.01),且观察组各指标均明显优于对照组(P < 0.01)。治疗后观察组病人眼动脉、视网膜中央动脉和睫状后动脉的收缩期峰值流速、舒张期流速、阻力指数均较治疗前明显改善(P < 0.01),且治疗后观察组各指标均优于对照组(P < 0.05~P < 0.01)。
      结论复方血栓通胶囊与胰激肽原酶肠溶片联合应用能够提高视网膜病变的临床治疗效果,值得临床推广。

       

      Abstract:
      ObjectiveTo explore the clinical effects of compound Xueshuantong capsule combined with pancreatic kininogenase enteric-coated tablets in the treatment of retinopathy.
      MethodsSixty patients diagnosed by non-proliferative retinopathy were randomly divided into the control group and observation group(30 cases each group).The control group was treated with pancreatic kininogenase enteric-coated tablets, and the observation group was treated with compound Xueshuantong capsule combined with pancreatic kininogenase intestine.The therapeutic effects, hemorheology and hemodynamics indexes between two groups were compared after treatment.
      ResultsThe total effective rate in observation group(96.67%) was slightly higher than that in control group(80.00%), but the difference was not statistially significant(P > 0.05).After treatment, the hematocrit, erythrocyte aggregation index, and whole blood high tangential viscosity in two groups were significantly improved compared with before treatment, and all indexes in observation group were significantly better than those in control group(P < 0.01).After treatment, the systolic peak velocity, diastolic velocity and resistance index of ophthalmic artery, central retinal artery and posterior ciliary artery in observation group were significantly improved compared with before treatment(P < 0.01), and all indexes in observation group were better than those in control group(P < 0.05 to P < 0.01).
      ConclusionsThe compound Xueshuantong capsule combined with pancreatic kininogenase enteric-coated tablet in the treatment of retinopathy can improve the clinical effect, which is worthy of clinical application.

       

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