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    曹晓玲. 中年高血压病人胰岛素抵抗与认知功能障碍的相关性研究[J]. 蚌埠医科大学学报, 2019, 44(2): 264-267. DOI: 10.13898/j.cnki.issn.1000-2200.2019.02.037
    引用本文: 曹晓玲. 中年高血压病人胰岛素抵抗与认知功能障碍的相关性研究[J]. 蚌埠医科大学学报, 2019, 44(2): 264-267. DOI: 10.13898/j.cnki.issn.1000-2200.2019.02.037
    shu
    CAO Xiao-ling. Study on the relationship between insulin resistance and cognition impairment in middle-aged hypertensive patients[J]. Journal of Bengbu Medical University, 2019, 44(2): 264-267. DOI: 10.13898/j.cnki.issn.1000-2200.2019.02.037
    Citation: CAO Xiao-ling. Study on the relationship between insulin resistance and cognition impairment in middle-aged hypertensive patients[J]. Journal of Bengbu Medical University, 2019, 44(2): 264-267. DOI: 10.13898/j.cnki.issn.1000-2200.2019.02.037
    shu

    中年高血压病人胰岛素抵抗与认知功能障碍的相关性研究

    Study on the relationship between insulin resistance and cognition impairment in middle-aged hypertensive patients

      摘要
    • 摘要:
      目的探讨中年高血压病人胰岛素抵抗与认知功能障碍之间的相关性。
      方法选取中年高血压病人96例作为研究对象，根据简明精神状态检查量表评分结果将病人分为认知功能障碍组40例和认知功能正常组56例，收集病人的一般资料，比较2组病人血压和相关生化指标，分析中年高血压病人认知功能障碍的影响因素。
      结果2组病人的文化程度、胰岛素抵抗指数、舒张压差异均有统计学意义（P < 0.05）。多因素logistic回归分析结果表明，文化程度、胰岛素抵抗指数是中年高血压病人认知功能障碍的独立影响因素（P < 0.01和P < 0.05）。
      结论胰岛素抵抗是中年高血压病人认知功能障碍的独立危险因素，临床中需对此加以重视。

       

      Abstract:
      ObjectiveTo explore the relationship between insulin resistance and cognition impairment in middle-aged hypertensive patients.
      MethodsNinety-six middle-aged hypertensive patients were divided into the cognition impairment group(40 cases) and normal cognitive function group(56 cases) according to the score of mini-mental state examination scale.The general data of two groups were collected, the blood pressure and biochemical indicators between two groups were compared, and the influencing factors of cognition impairment were analyzed in middle-aged hypertensive patients.
      ResultsThe differences of the cultural level, insulin resistance index and diastolic blood pressure between two groups were statistically significant(P < 0.05).The results of multiple factors regression analysis showed that the cultural level and insulin resistance index were the independent influencing factors of cognition impairment in middle-aged hypertensive patients(P < 0.01 and P < 0.05).
      ConclusionsThe insulin resistance is the independent risk factor of cognition impairment in middle-aged hypertensive patients, which should be paid attention to.

       

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