ObjectiveTo explore the relationship between insulin resistance and cognition impairment in middle-aged hypertensive patients.

MethodsNinety-six middle-aged hypertensive patients were divided into the cognition impairment group(40 cases) and normal cognitive function group(56 cases) according to the score of mini-mental state examination scale.The general data of two groups were collected, the blood pressure and biochemical indicators between two groups were compared, and the influencing factors of cognition impairment were analyzed in middle-aged hypertensive patients.

ResultsThe differences of the cultural level, insulin resistance index and diastolic blood pressure between two groups were statistically significant(P < 0.05).The results of multiple factors regression analysis showed that the cultural level and insulin resistance index were the independent influencing factors of cognition impairment in middle-aged hypertensive patients(P < 0.01 and P < 0.05).

ConclusionsThe insulin resistance is the independent risk factor of cognition impairment in middle-aged hypertensive patients, which should be paid attention to.