ObjectiveTo analyze the risk factors of catheter-related infection (CRI) in acute leukemia patients treated with peripherally inserted central catheter (PICC) to provide the reasonable strategies for clinical nursing care.

MethodsThe clinical data of 132 acute leukemia patients treated with PICC were successfully collected.The general clinical data, length of catheterization, number of puncture, application of chemotherapy drugs, use of hormone and immune function in all patients were analyzed.The correlation of CRI occurrence with season, and secretion culture results of CRI patients were analyzed.

ResultsAmong 132 patients, 21 cases with CRI were found, and the infection rate of which was 15.91%.The CRI occurrence was not related to the classification of acute leukemia, gender and age (P>0.05).The infection rates in patients with long time of catheter indwelling, more punctural times, chemotherapy drug use, history of use hormone and low immune function, and at summer were higher than that in patients with short time of catheter indwelling, few punctural time, no use of chemotherapy drug, no hormone history and normal immune function, and at spring, autumn and winter (P < 0.05 to P < 0.01).Among 21 CRI patients, the secretion in 2 cases were not examined.The secretion culture results of the rest 19 patients showed that the proportions of Glucose aureus, Klebsiella bacillus, corynebacterium and other bacteria infection were 52.6%, 21.1%, 21.1% and 5.2%, respectively.

ConclusionsShortening the PICC catheter indwelling time, reducing the punctural time, strengthening the immune treatment, controlling the use of hormone and choosing the antibiotics based on main coccus infection for preventive treatment can avoid and control the CRI in acute leukemia patients treated with PICC.