氟哌噻吨美利曲辛治疗老年糖尿病性胃肠功能紊乱伴焦虑抑郁病人的效果观察

刘绪和; 梁冰

doi:10.13898/j.cnki.issn.1000-2200.2019.04.008

氟哌噻吨美利曲辛治疗老年糖尿病性胃肠功能紊乱伴焦虑抑郁病人的效果观察

刘绪和,
梁冰

Effect of Deanxit in the treatment of anxiety and depression in elderly diabetic patients complicated with gastrointestinal dysfunction

摘要

摘要:
目的观察氟哌噻吨美利曲辛辅助治疗伴焦虑抑郁的老年糖尿病性胃肠功能紊乱病人的临床疗效。
方法将104例确诊的伴焦虑抑郁的老年糖尿病性胃肠功能紊乱病人随机分为观察组及对照组，每组52例。2组病人均给予对应的药物，观察组在此基础上加服氟哌噻吨美利曲辛1片/日，观察8周，治疗前后对所有病人均进行临床症状评分、治疗总有效率、汉密尔顿抑郁量表、汉密尔顿焦虑量表测评。
结果观察组临床症状改善总有效率86.5%，优于对照组的63.5%（P < 0.05），观察组病人治疗8周后焦虑和抑郁评分均明显低于对照组（P < 0.01）。
结论对于伴有焦虑抑郁的老年糖尿病胃肠功能紊乱病人在传统治疗的基础上加用氟哌噻吨美利曲辛可显著改善其精神及躯体症状，值得推广应用。

Abstract:
ObjectiveTo observe the clinical efficacy of flupentixol and melitracen in the treatment of anxiety and depression in elderly diabetic patients complicated with gastrointestinal dysfunction.
MethodsOne hundred and four elderly diabetic patients with anxiety and depression complicated with gastrointestinal dysfunction were randomly divided into the observation group and control group(52 cases each group).Two groups were treated with corresponding drugs, and the observation group was additionally treated with flupentixol and melitracen, 1 tablet per day, for 8 weeks.The clinical symptom scores before and after treatment, total effective rate, Hamilton Depression Scale(HAMD) score and Hamilton Anxiety Scale(HAMA) after treatment in two groups were analyzed.
ResultsThe total effective rate of improvement of clinical symptom in observation group(86.5%) was better than that in control group(63.5%)(P < 0.05).The score of anxiety and depression in observation group was significantly lower than that in control group(P < 0.01).
ConclusionsThe treatment of anxiety and depression in elderly diabetic patients complicated with gastrointestinal dysfunction with flupentixol and melitracen based on traditional therapy can significantly improve their mental physical symptoms, and which is worthy of promotion.

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