糖尿病足严重程度的相关因素分析

胡慧萍; 陈明卫

doi:10.13898/j.cnki.issn.1000-2200.2019.07.013

糖尿病足严重程度的相关因素分析

Related factors analysis of the severity of diabetic foot

摘要

摘要:
目的探讨影响糖尿病足严重程度（瓦格纳分级）的相关因素。
方法收集305例住院糖尿病足病人的相关资料，根据瓦格纳（Wagner）分级将其分为5组，1级81例，2级62例，3级82例，4级72例，5级8例。对影响糖尿病足Wagner分级的因素进行分析。
结果糖尿病足病人的Wagner分级越高，最大溃疡面积越大（P < 0.05），中性粒细胞、尿酸、超敏C反应蛋白水平越高（P < 0.05~P < 0.01），血红蛋白和白蛋白水平越低（P < 0.05和P < 0.01），并发糖尿病周围神经病的频率增高（P < 0.05）。Spearman等级相关分析显示，Wagner分级程度与周围神经病、最大溃疡面积、中性粒细胞计数、尿酸水平呈正相关，与血红蛋白、白蛋白呈负相关。
结论对于糖尿病足病人应积极控制感染，降低尿酸水平、治疗神经病变、保持好的营养状态，防止病情进一步进展。

Abstract:
ObjectiveTo explore the related influencing factors of the severity of diabetic foot(Wagner classification).
MethodsThe relevant data of 305 hospitalized patients with diabetic foot were analyzed.According to Wagner's classification, grade 1 in 81 cases, grade 2 in 62 cases, grade 3 in 82 cases, grade 4 in 72 cases and grade 5 in 8 cases were identified.The factors influencing Wagner classification of diabetic foot were analyzed.
ResultsThe higher the Wagner classification of diabetic foot patients was, the larger the maximum ulcer area was(P < 0.05), the higher the levels of neutrophils, uric acid and hypersensitive C-reactive protein were (P < 0.05 to P < 0.01), the lower the levels of hemoglobin and albumin were (P < 0.05 and P < 0.01), and the higher the frequency of diabetic peripheral neuropathy was (P < 0.05).The results of Spearman grade analysis showed that the degree of Wagner classification was positively correlated with the peripheral neuropathy, maximum ulcer area, neutrophil count and uric acid level, and negatively correlated with the levels of hemoglobin and albumin.
ConclusionsFor diabetic foot patients, actively controlling infection, reducing uric acid level, treating neuropathy and maintaining a good nutritional status can prevent further progress of the disease.

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