ObjectiveTo observe the application effects of entropy index combined with muscle relaxation monitoring in induction period of general anesthesia in elderly patients.

MethodsSixty patients scheduled by upper abdominal surgery were divided into the muscle relaxant monitoring group(group Ⅰ), entropy index monitoring group(group Ⅱ) and routine monitoring group(group Ⅲ) according to "American Society of anesthesiologists(ASA) grade Ⅱ to Ⅲ" using the random number table method(20 cases each group).The systolic pressure, diastolic pressure, heart rate and time from finishing muscle relaxant injection to tracheal intubation in three groups were recorded before anesthesia(T₀), after induction(T₁), tracheal intubation(T₂), after 1min of intubation(T₃)and after 5min of intubation(T₄).

ResultsCompared with the group Ⅲ, the increasing degrees of systolic pressure and heart rate in group Ⅰ and group Ⅱ at T₂ and T₃ were less(P < 0.05 to P < 0.01).Compared with the groupⅠ, the increasing degrees of systolic pressure and heart rate in group Ⅱ at T₂ and T₃ were more(P < 0.05), and the differences of the systolic pressure and heart rate between group Ⅰ and group Ⅱ at T₄were not statistically significant(P>0.05).Compared with group Ⅲ at T₀ and T₁, the increasing degrees of systolic pressure and heart rate were significant at T₂ and T₃(P < 0.05 to P < 0.01).Among the three groups, the differences of the diastolic blood pressure at different time points were not statistically significant(P>0.05).The duration from finishing muscle relaxant injection to tracheal intubation in group Ⅰ, group Ⅱ and group Ⅲ gradually decreased(P < 0.05 to P < 0.01).

ConclusionsThe monitoring of entropy index combined with muscle relaxation during general anesthesia induction period in elderly patients can maintain the smooth of hemodynamics, and the tracheal intubation condition and degree of glottis exposure are better.