肿瘤病人营养状况调查及其影响因素分析

    Investigation of the nutritional status and its influencing factors in tumor patients

    • 摘要:
      目的对肿瘤病人营养状况进行调查并分析其影响因素。
      方法应用患者主观整体评估(patient-generated subjective global assessment,PG-SGA)法对2014年2月至2016年8月在安徽省肿瘤医院放化疗科住院治疗的996例肿瘤病人入院48 h内完成营养评估。并将其分为营养状况良好(PG-SGA A级)、可疑或中度营养不良(PG-SGA B级)、重度营养不良(PG-SGA C级)3组;其中PG-SGA A级归为无营养不良组、PG-SGA B级与PG-SGA C级归为营养不良组,并收集病人基本信息及各项客观营养指标,分析各因素与营养不良的相关性。
      结果共959例恶性肿瘤病人纳入研究,其中PG-SGA A级366例(38.2%)、PG-SGA B级268例(28.0%)、PG-SGA C级325例(33.9%),营养不良发生率为61.8%。多因素logistic回归分析结果显示:放疗(OR=1.629)、体质量指数大(OR=11.769)、低蛋白血症(OR=10.982)和非利手(或非损伤手)握力(OR=1.060)是恶性肿瘤发生营养不良的独立危险因素(P < 0.05~P < 0.01),而女性(OR=0.164)、年轻(OR=0.958)、无口干(OR=0.038)、无早饱(OR=0.053)是保护因素(P < 0.01)。
      结论营养不良是恶性肿瘤病人常见的问题,应尽早对恶性肿瘤病人进行营养筛查。

       

      Abstract:
      ObjectiveTo investigate the nutritional status, and analyze the influencing factors in cancer patients.
      MethodsThe nutritional status of 996 tumor patients from the departments of radiotherapy and chemotherapy of Anhui Provincial Tumor Hospital from February 2014 to August 2016 were evaluated using the patient-generated subjective global assessment(PG-SGA) within 48 h of admission.The patients were divided into the good nutrition(stage PG-SGA A) group, suspected or moderate malnutrition(stage PG-SGA B) group and severe malnutrition(stage PG-SGA C) group.The stage PG-SGA A was classified as the non-malnutrition group, and the stage PG-SGA B and C were classified as malnutrition group, the basic information and various objective nutritional indicators of patients were collected to analyze the correlation between each factor and malnutrition.
      ResultsAmong 959 tumor patients, the stage PG-SGA A in 366 cases(38.16%), stage PG-SGA B in 268 cases(27.95%) and stage PG-SGA C in 325 cases(33.89%) were identified, and the incidence rate of malnutrition was 61.84%.The results of multivariate logistic regression analysis showed that the radiotherapy(OR=1.629), booly mass index(OR=11.769), hypoproteinemia(OR=10.982) and grip strength(OR=1.060) were the independent risk factors of malnutrition(P < 0.05 to P < 0.01), and the female(OR=0.164), youth(OR=0.958), no dry mouth(OR=0.038), and premature satiation(OR=0.053) were the protective factors(P < 0.01).
      ConclusionsMalnutrition is a common problem in patients with malignant tumors.The nutritional screening should be conducted as early as possible in patients with malignant tumors.

       

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