Objective To analyze the clinical characteristics of 74 patients with corona virus disease 2019(COVID-19).

Methods The clinical characteristics of 74 pateints with COVID-19 from January 22 to March 4, 2020 from the First Affiliated Hospital of Bengbu Medical College were retrospectively analyzed, and the clinical characteristics were compared between common type and severe type patients.

Results Among 74 patients, 35 cases were the common type, and 39 cases were severe/critical type cases.There were high number of familial cluster(37 cases, 50.0%).The age, and rates of complicated with other basic diseases and complicated with two or more basic diseases in severe/critical patients were higher than those in common patients(P < 0.05 to P < 0.01).In terms of clinical symptoms, the time from onset to see doctor in severe/critical patients was longer than that in common patients, and the highest body temperature, incidence rates of chest tightness and dyspnea in severe/critical patients were higher than those in common patients(P < 0.05 to P < 0.01).In terms of laboratory examination, the absolute value of leucocyte and neutrophil, percentage of neutrophil, C-reactive protein and interleukin-6 in severe/critical patients were higher compared with those in common patients, and the absolute value of lymphocyte, percentage of lymphocyte and albumin in severe/critical patients were lower compared with those in common patients(P < 0.05 to P < 0.01).The patchy ground glass opacity in chest CT of all cases were found.

Conclusions The number of familial clustering cases of COVID-19 in Bengbu city is more, and the elderly complicated with more basic diseases and systemic inflammatory response are the clinical characteristics of severe/critical patients.