ObjectiveTo explore the clinical value of conventional ultrasound breast imaging reporting and data system(BI-RADS) classification combined with real-time shear wave elastography in the diagnosis of triple negative breast cancer.

MethodsSeventy-one hospitalized patients with breast cancer confirmed by pathology were investigated, and 25 cases with triple negative breast cancer and 46 cases without triple negative breast cancer were divided into the TNBC group and non-TNBC group, respectively.The conventional ultrasonic image characteristics between two groups were observed and compared, the real-time shear wave elastography in two groups was performed to measure the elastic Young's modulus value, and the BI-RADS classification in two groups was adjusted to compare the diagnostic accuracy before and after combined diagnosis.

ResultsIn conventional ultrasound, compared with non-triple negative breast cancer, the benign tumor features in triple negative breast cancer were found, the burr rate, echo attenuation rate and microcalcification rate at the edge of tumor were higher, and the rate of lymph node metastasis was lower(P < 0.05 to P < 0.01).The values of Emean and Emax in real-time shear wave elastography in TNBC group were lower than those in non-TNBC group(P < 0.01).After the combined application of real-time shear wave elastography for BI-RADS classification was adjusted, the diagnostic sensitivity and missed diagnosis rate for triple negative breast cancer were 92% and 8%, respectively.

ConclusionThe conventional ultrasound combined with real-time shear wave elastography in the diagnosis of triple negative breast cancer can reduce the missed diagnosis rate of BI-RADS classification, and has important diagnostic value in clinical application.