卵巢癌发生的高危因素分析

    Analysis of the risk factors of ovarian cancer

    • 摘要:
      目的探讨卵巢癌发生的危险因素。
      方法选取卵巢癌病人90例(观察组)及健康志愿者270例(对照组),调查2组临床资料。
      结果2组年龄、婚姻状况及文化程度比较差异无统计学意义(P>0.05);观察组产次为0次、月经周期>30 d、初潮年龄 < 13岁、有人工流产史、卵巢癌家族史的比例分别为56.67%、46.67%、62.22%、36.67%和23.33%,高于对照组(P < 0.05~P < 0.01);logistic回归分析显示,产次≥2次、初潮年龄≥13岁是卵巢癌发生的保护因素(P < 0.01),月经周期>30 d、人工流产史和卵巢癌家族史是卵巢癌发生的危险因素(P < 0.01)。
      结论卵巢癌的发生受多因素影响,应根据相关危险因素制定针对性措施进行预防。

       

      Abstract:
      ObjectiveTo explore the risk factors of ovarian cancer.
      MethodsNinety patients with ovarian cancer and 270 healthy volunteers were divided into the observation group and control group, respectively.The clinical data in two groups were investigated.
      ResultsThe differences of the age, marital status and educational level between two groups were not statistically significant(P>0.05).The ratios of the no delivery, menstrual cycle >30 days, menarche age < 13 years old, abortion history and ovarian cancer family history in observation group were 56.67%, 46.67%, 62.22%, 36.67% and 23.33%, respectively, and which were significantly higher than those in control group(P < 0.05 to P < 0.01).The results of logistic regression analysis showed that the delivery times ≥2 and menarche age ≥13 years were the protective factors of ovarian cancer(P < 0.01), and the menstrual cycle >30 days, abortion history and family history of ovarian cancer were the risk factors of ovarian cancer(P < 0.01).
      ConclusionsThe occurrence of ovarian cancer is influenced by many factors, and the preventive measures should be made according to the relevant risk factors.

       

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