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    葛宁, 刘浩武, 康亚辉, 张洪波. 食管癌术后调强放疗致放射性胃炎的影响因素分析[J]. 蚌埠医科大学学报, 2020, 45(8): 1004-1007. DOI: 10.13898/j.cnki.issn.1000-2200.2020.08.004
    引用本文: 葛宁, 刘浩武, 康亚辉, 张洪波. 食管癌术后调强放疗致放射性胃炎的影响因素分析[J]. 蚌埠医科大学学报, 2020, 45(8): 1004-1007. DOI: 10.13898/j.cnki.issn.1000-2200.2020.08.004
    shu
    GE Ning, LIU Hao-wu, KANG Ya-hui, ZHANG Hong-bo. Analysis of the influencing factors of radiation gastritis induced by intensity-modulated radiotherapy after esophageal cancer operation[J]. Journal of Bengbu Medical University, 2020, 45(8): 1004-1007. DOI: 10.13898/j.cnki.issn.1000-2200.2020.08.004
    Citation: GE Ning, LIU Hao-wu, KANG Ya-hui, ZHANG Hong-bo. Analysis of the influencing factors of radiation gastritis induced by intensity-modulated radiotherapy after esophageal cancer operation[J]. Journal of Bengbu Medical University, 2020, 45(8): 1004-1007. DOI: 10.13898/j.cnki.issn.1000-2200.2020.08.004
    shu

    食管癌术后调强放疗致放射性胃炎的影响因素分析

    Analysis of the influencing factors of radiation gastritis induced by intensity-modulated radiotherapy after esophageal cancer operation

      摘要
    • 摘要:
      目的分析食管癌术后调强放疗致急性放射性胃炎的相关因素。
      方法采用剂量-体积直方图计算60例食管癌术后调强放疗病人的胸腔胃最大剂量(Dmax)、胸腔胃平均剂量(Dmean)、不同位置胸腔胃体积、胃受照体积百分比(V5、V10、V20、V30、V40、V45、V50)、胃受照体积(aV5、aV10、aV20、aV30、aV40、aV45、aV50)。分析不同位置胸腔胃体积差别。ROC曲线确定最佳临界值，logistic多因素分析确定预测指标。
      结果右侧胸腔胃体积与左侧、纵隔胸腔胃体积比较差异有统计学意义(P < 0.05)。V50、aV50是预测急性放射性胃炎的指标(P < 0.01)。
      结论食管癌术后调强放疗计划评估中需要重点关注胸腔胃V50和aV50的评估。

       

      Abstract:
      ObjectiveTo analyze the related factors of acute radiation gastritis induced by intensity-modulated radiotherapy after esophageal cancer surgery.
      MethodsThe maximum dose(Dmax), mean dose(Dmean), intrathoracic stomach volume in different locations, illuminated volume percent(V5, V10, V20, V30, V40, V45 and V50), intrathoracic stomach illuminated volume(aV5, aV10, aV20, aV30, aV40 aV45 and aV50) in 60 esophageal cancer patients treated with postoperative intensity modulated cancer radiotherapy were calculated using the dose volume histogram.The differences of intrathoracic stomach volume in different locations were analyzed.The optimal critical value was determined by ROC curve, and the predictive index was determined by logistic multivariate analysis.
      ResultsThe differences of the intrathoracic stomach volume between the right side and left side, mediastinum were statistically significant(P < 0.05).The V50 and aV50 were the indicator to predict acute radioation gastritis(P < 0.01).
      ConclusionsIn the evaluation of postoperative induced by intensity-modulated radiotherapy plan for esophageal cancer, the evaluation of V50 and aV50 in pleural and gastric areas should be greatly focused on.

       

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