ObjectiveTo investigate the correlation between carotid plaque characteristics, risk factors, and neutrophil-to-lymphocyte ratio(NLR) in patients with acute ischemic stroke.

MethodsThe clinical data of 205 hospitalized patients with acute ischemic stroke were retrospective analyzed.According to the results of cervical vascular ultrasound, the patients were divided into the plaque group(including hard plaque group, soft plaque group and mixed plaque group) and non-plaque group.The patient's clinical data, laboratory test indicators, and neutrophil-to-lymphocyte ratio were compared, and the independent risk factors of carotid plaque formation were analyzed using logistic regression.

ResultsThe smoking composition ratio, endometrial thickness, total cholesterol, low density lipoprotein, blood glucose, white blood cells, neutrophils and NLR in plaque group were higher than those in non-plaque group(P < 0.05 to P < 0.01).The results of multivariate logistic regression analysis showed that the blood glucose, white blood cells, neutrophils, intimal thickness and NLR were the independent risk factors of carotid plaque formation(P < 0.05 to P < 0.01).The differences of the gender, low-density lipoprotein, white blood cells, neutrophils, intimal thickness and NLR among the hard plaque group, mixed plaque group and soft plaque group were statistically significant(P < 0.05 to P < 0.01).

ConclusionsThe smoking, hyperlipidemia and blood glucose are related to the carotid plaque and nature, and the NLR is also related to the formation and nature of carotid plaque as a new inflammatory indicator.