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    双能量能谱CT物质定量分析技术对胰腺脂肪沉积的诊断价值

    Diagnostic value of dual-energy spectral CT material quantitative analysis in pancreatic fat deposition

      摘要
    • 摘要:
      目的探讨双能量能谱CT物质定量分析技术对胰腺脂肪沉积的诊断价值。
      方法选取临床诊断为肥胖症、高血糖、脂肪肝等代谢综合征症候群病人35例（观察组），在最佳KeV值单能量图像上，分别测定胰腺头、体、尾部的CT值；在脂肪-水物质图像上，分别测定胰腺头、体、尾部的脂肪含量；获得胰腺各部组织的能谱曲线，并做出平均能谱曲线。将该结果与30例因体检或其他疾病行腹部CT扫描的病人（对照组）所测定的脂肪含量值进行对照研究。
      结果观察组35例中8例体质量指数（BMI）正常，其余均为超重或肥胖；观察组中胰腺平均CT值随着BMI增高呈下降趋势，而平均脂肪含量值随BMI增高呈上升趋势（P < 0.01）；观察组胰腺组织的能量CT值及水含量值均明显低于对照组，脂肪含量值明显高于对照组（P < 0.01）。
      结论双能量能谱CT定量分析技术可客观、定量地描述胰腺中的脂肪沉积，为临床早期诊断、早期治疗提供更加有价值的信息。

       

      Abstract:
      ObjectiveTo explore the diagnostic value of dual-energy spectral CT material quantitative analysis for pancreatic fat deposition.
      MethodsA total of 35 patients with metabolic syndrome, such as obesity, hyperglycemia and fatty liver, were selected as the observation group.The CT values of the head, body and tail of pancreas were measured on the single energy image of optimal keV value.The fat contents of the head, body and tail of pancreas were determined on the fat-water material image.The spectral curves of pancreatic tissues were obtained to make the average spectral curves.The results were compared with the fat contents measured in 30 patients who underwent abdominal CT scan for physical examination or other diseases in the control group.
      ResultsAmong 35 cases in the observation group, 8 cases were found with normal body mass index, and the rest were overweight or obesity.The average CT value of pancreas decreased with the increase of body mass index (P < 0.01), while the average fat content increased with the increase of body mass index(P < 0.01).The energy CT value and water content of pancreatic tissues in observation group were significantly lower than those in control group, and the fat content was significantly higher than that in control group(P < 0.01).
      ConclusionsDual-energy spectral CT quantitative analysis can objectively and quantitatively describe the fat deposition in pancreas, and provide more valuable informations for early diagnosis and treatment in clinic.

       

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