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    王书芹, 朱广辉. 能谱CT在结直肠癌分化程度中的应用价值研究[J]. 蚌埠医科大学学报, 2021, 46(1): 29-32. DOI: 10.13898/j.cnki.issn.1000-2200.2021.01.008
    引用本文: 王书芹, 朱广辉. 能谱CT在结直肠癌分化程度中的应用价值研究[J]. 蚌埠医科大学学报, 2021, 46(1): 29-32. DOI: 10.13898/j.cnki.issn.1000-2200.2021.01.008
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    WANG Shu-qin, ZHU Guang-hui. Aapplication value of spectral CT in the evaluation of the differentiation degree of colorectal cancer[J]. Journal of Bengbu Medical University, 2021, 46(1): 29-32. DOI: 10.13898/j.cnki.issn.1000-2200.2021.01.008
    Citation: WANG Shu-qin, ZHU Guang-hui. Aapplication value of spectral CT in the evaluation of the differentiation degree of colorectal cancer[J]. Journal of Bengbu Medical University, 2021, 46(1): 29-32. DOI: 10.13898/j.cnki.issn.1000-2200.2021.01.008
    shu

    能谱CT在结直肠癌分化程度中的应用价值研究

    Aapplication value of spectral CT in the evaluation of the differentiation degree of colorectal cancer

      摘要
    • 摘要:
      目的研究256排Revolution能谱CT各参数在结直肠癌分化程度中的应用价值。
      方法选取50例通过肠镜或病理确诊的结直肠癌病人，于手术前行GSI能谱CT平扫及双期扫描，通过GSI Viewer软件获得相关能谱图像，并在病灶内勾画出合适的感兴趣区，测量病灶的碘基值（IC）、水浓度、有效原子序数（Eff-Z）、标准化碘浓度（NIC）及能谱曲线斜率（K）。根据病理结果，将50例病人分为低分化组与中高分化组，比较2组各能谱参数，并采用ROC曲线分析各能谱参数的诊断能力。
      结果50例病人中高分化组32例，低分化组18例。低分化组肿瘤的淋巴结转移高于中高分化组（P < 0.05）。2组动脉期IC、NIC、水浓度、Eff-Z、K及静脉期水浓度、Eff-Z差异均无统计学意义（P>0.05），低分化组静脉期IC、NIC、K均高于中高分化组（P < 0.05）。静脉期IC、NIC、K诊断结直肠癌分化程度的曲线下面积分别为0.77、0.81、0.79，诊断阈值分别为18.31、0.56、2.07，敏感性分别为88.3%、83.3%、88.9%，特异性分别为62.5%、75.0%、68.7%。
      结论能谱CT参数IC、NIC以及K在结直肠癌分化程度中有较高的应用价值。

       

      Abstract:
      ObjectiveTo investigate the application value of each parameter of 256-row Revolution spectral CT in evaluating the differentiation degree of colorectal cancer.
      MethodsFifty patients with colorectal cancer diagnosed by colonoscopy or pathology were selected, and detected using the GSI spectral CT plain scan and dual-phase scan before surgery.The relevant spectral images were obtained through GSI Viewer software, the appropriate region of interest was delineated in the lesion, and the iodine base value(IC), water concentration, effective atomic number(Eff-Z), normalized iodine concentration(NIC) and energy spectral slope(K) of the lesion were measured.According to the pathological results, 50 patients were divided into the low differentiation group and middle-high differentiation group.The spectral parameters were compared between two groups, and the diagnostic ability of each spectral parameter were analyzed using the receiver operating characteristic curve.
      ResultsAmong 50 patients, 32 cases in middle-high differentiation group and 18 cases in low differentiation group were identified.The lymph node metastasis in low differentiation group was higher than that in middle-high differentiation group(P < 0.05).There was no statistical significance in the IC, NIC, water concentration, Eff-Z and K of arterial phase, and water concentration and Eff-Z of venous phase between two groups(P>0.05).The IC, NIC and K of venous phase in low differentiation group were higher than those in middle-high differentiation group(P < 0.05).The area under the curve, diagnostic threshold, sensitivity and specificity of venous phase IC, NIC, and K were (0.77, 0.81 and 0.79), (18.31, 0.56 and 2.07), (88.3%, 83.3% and 88.9%) and (62.5%, 75.0% and 68.7%), respectively.
      ConclusionsThe parameters IC, NIC and K of spectral CT have high values in evaluating the differentiation of colorectal cancer.

       

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