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    刘双池, 谈燚, 庞青, 金浩, 范龙飞, 段家康. 腹腔镜肝切除在肝细胞肝癌中的应用价值分析[J]. 蚌埠医科大学学报, 2021, 46(5): 583-586. DOI: 10.13898/j.cnki.issn.1000-2200.2021.05.006
    引用本文: 刘双池, 谈燚, 庞青, 金浩, 范龙飞, 段家康. 腹腔镜肝切除在肝细胞肝癌中的应用价值分析[J]. 蚌埠医科大学学报, 2021, 46(5): 583-586. DOI: 10.13898/j.cnki.issn.1000-2200.2021.05.006
    shu
    LIU Shuang-chi, TAN Yi, PANG Qing, JIN Hao, FAN Long-fei, DUAN Jia-kang. Application value of laparoscopic hepatectomy in hepatocellular carcinoma[J]. Journal of Bengbu Medical University, 2021, 46(5): 583-586. DOI: 10.13898/j.cnki.issn.1000-2200.2021.05.006
    Citation: LIU Shuang-chi, TAN Yi, PANG Qing, JIN Hao, FAN Long-fei, DUAN Jia-kang. Application value of laparoscopic hepatectomy in hepatocellular carcinoma[J]. Journal of Bengbu Medical University, 2021, 46(5): 583-586. DOI: 10.13898/j.cnki.issn.1000-2200.2021.05.006
    shu

    腹腔镜肝切除在肝细胞肝癌中的应用价值分析

    Application value of laparoscopic hepatectomy in hepatocellular carcinoma

      摘要
    • 摘要:
      目的探讨腹腔镜肝切除术在肝细胞肝癌治疗中的近期临床应用价值。
      方法对169例术后病理诊断为肝细胞肝癌的病人临床资料进行回顾性分析，比较腹腔镜手术与开腹手术在治疗肝细胞肝癌的近期临床效果。
      结果腹腔镜组手术时长高于开腹组（P < 0.05），术中出血量、术后住院时间均明显低于开腹组（P < 0.01）。术后镇痛药使用率腹腔镜组低于开腹组（P < 0.01）。腹腔镜组术后第3、7天外周血白蛋白水平高于开腹组（P < 0.01），术后第3、7、30天外周血丙氨酸氨基转移酶、天门冬氨酸氨基转移酶水平均低于开腹组（P < 0.01）。2组术后1个月白蛋白水平、术后总体并发症发生率、术后总胆红素改变及术后2年内肿瘤复发率差异均无统计学意义（P>0.05）。
      结论腹腔镜手术治疗肝细胞肝癌与开腹手术的治疗效果相近，且病人住院时间更短、恢复更快。

       

      Abstract:
      ObjectiveTo explore the clinical value of laparoscopic hepatectomy in the treatment of hepatocellular carcinoma.
      MethodsThe clinical data of 169 patients with the pathological diagnosis of hepatocellular carcinoma were analyzed retrospectively, and the clinical effects of laparoscopy and laparotomy in the treatment of hepatocellular carcinoma were compared.
      ResultsThe operation time in the laparoscopy group was longer than that in the laparotomy group(P < 0.05), while the intraoperative blood loss and postoperative hospital stay in the laparoscopy group were significantly lower than those in the laparotomy group(P < 0.01).The utilization rate of postoperative analgesics in the laparoscopy group was significantly lower than that in the laparotomy group(P < 0.01).The levels of peripheral blood albumin in the laparoscopy group were higher than that in open group on the 3rd and 7th day after operation.The levels of ALT and AST in laparoscopy group were lower than those in the laparotomy group on the 3th, 7th and 30th day after operation.There was no significant difference in serum albumin levels, overall incidence of postoperative complications, total bilirubin changes and tumor recurrence rate within 2 years after operation between the two groups.
      ConclusionsLaparoscopic surgery for hepatocellular carcinoma has the same therapeutic effect as open surgery with shorter hospital stay and faster recovery.

       

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