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    阻塞性睡眠呼吸暂停综合征并功能性便秘的相关性研究

    Study on the correlation of obstructive sleep apnea syndrome with functional constipation

      摘要
    • 摘要:
      目的对阻塞性睡眠呼吸暂停综合征（OSAS）并功能性便秘（FC）的相关性进行分析研究。
      方法选取OSAS病人185例作为研究对象，按照是否合并FC分为观察组（n=82）和对照组（n=103）。统计并比较2组病人的睡眠呼吸暂停低通气指数（AHI）、睡眠参数、睡眠结构和体质量指数（BMI）。
      结果观察组AHI、BMI值均显著高于对照组（56.9±17.34）vs（32.3±11.09）（P < 0.01）。中重度FC+OSAS组病人的AD均较对照组显著增高（P < 0.01），minSaO2%则较对照组显著降低（P < 0.01）。中度FC+OSAS组病人睡眠1+2期比例、呼吸相关微觉醒指数分别为（79.6±11.7）（30.1±10.4），均显著高于对照组（P < 0.01）。重度FC+OSAS组病人睡眠1+2期比例、呼吸相关微觉醒指数分别为（82.3±6.7）（35.3±17.6），均显著高于对照组（P < 0.01）。中度FC+OSAS组病人慢波睡眠比例、睡眠REM期比例值分别为（8.2±7.3）（9.6±2.5），重度FC+OSAS组病人慢波睡眠比例、睡眠REM期比例值分别为（6.1±5.2）（8.7±1.8），均显著低于对照组（P < 0.01）。
      结论FC和OSAS密切相关。

       

      Abstract:
      ObjectiveTo investigate the correlation between obstructive sleep apnea syndrome(OSAS) and functional constipation(FC).
      MethodsOne hundred and eighty-five patients with OSAS were divided into the observation group(82 OSAS cases complicated with FC) and control group(103 cases).The apnea-hypopnea index(AHI), sleep parameters, sleep structure and body mass index(BMI) were comapred between two groups.
      ResultsThe AHI and BMI values in observation group were significantly higher than those in control group(56.9±17.34) vs(32.3±11.09)(P < 0.01).The AD in moderate and severe FC+OSAS group was significantly higher than that in control group (P < 0.01), while minSaO2% was significantly lower than that in control group (P < 0.01).In the moderate(FC+OSAS) group, the proportion of sleep stage 1+2 and respiration-related microarousal index were(79.6±11.7) and (30.1±10.4), respectively, which were significantly higher than those in control group(P < 0.01).In the severe(FC+OSAS) group, the proportion of sleep stage 1+2 and respiration related microarousal index were(82.3±6.7) and (35.3±17.6), respectively, which were significantly higher than those in control group(P < 0.01).The proportions of slow-wave sleep and REM sleep in the moderate and severe (FC+OSAS) groups were(8.2±7.3) and(9.6±2.5) and(6.1±5.2) and(8.7±1.8), respectively, and which were significantly lower than those in control group(P < 0.01).
      ConclusionsFC is closely related to OSAS.

       

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