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    汪莲, 陈先侠. 白蛋白及血浆扩容治疗早发型子痫前期的临床疗效[J]. 蚌埠医科大学学报, 2022, 47(3): 353-355. DOI: 10.13898/j.cnki.issn.1000-2200.2022.03.020
    引用本文: 汪莲, 陈先侠. 白蛋白及血浆扩容治疗早发型子痫前期的临床疗效[J]. 蚌埠医科大学学报, 2022, 47(3): 353-355. DOI: 10.13898/j.cnki.issn.1000-2200.2022.03.020
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    WANG Lian, CHEN Xian-xia. Retrospective controlled study on the clinical effect of albumin and plasma volume expansion in the treatment of early onset preeclampsia[J]. Journal of Bengbu Medical University, 2022, 47(3): 353-355. DOI: 10.13898/j.cnki.issn.1000-2200.2022.03.020
    Citation: WANG Lian, CHEN Xian-xia. Retrospective controlled study on the clinical effect of albumin and plasma volume expansion in the treatment of early onset preeclampsia[J]. Journal of Bengbu Medical University, 2022, 47(3): 353-355. DOI: 10.13898/j.cnki.issn.1000-2200.2022.03.020
    shu

    白蛋白及血浆扩容治疗早发型子痫前期的临床疗效

    Retrospective controlled study on the clinical effect of albumin and plasma volume expansion in the treatment of early onset preeclampsia

      摘要
    • 摘要:
      目的探讨白蛋白及血浆扩容在早发型子痫前期中的治疗效果。
      方法回顾性分析120例早发型子痫前期单胎孕妇的临床资料，按照扩容不同分为血浆组(40例)、白蛋白组(40例)，40例未予扩容治疗的病人作为对照组。比较3组分娩孕周、围生儿不良结局和母体并发症发生率。
      结果扩容组(白蛋白组、血浆组)分娩孕周较对照组延长(P < 0.05)，胎儿生长受限发生率低于对照组(P < 0.05)。血浆组胎盘早剥、产后出血发生率均低于对照组(P < 0.05)，血浆组肾功能损伤发生率低于白蛋白组(P < 0.05)。
      结论白蛋白及血浆扩容治疗早发型子痫前期效果明显，能延长分娩孕周，改善围生儿结局，不增加母体并发症。

       

      Abstract:
      ObjectiveTo investigate the effect of albumin and plasma volume expansion in the treatment of early onset preeclampsia.
      MethodsThe clinical data of 120 singleton pregnant women with early onset preeclampsia were analyzed retrospectively, and divided into plasma group(volume expanded with plasma, 40 cases), albumin group(volume expanded with albumin, 40 cases)and control group(no volume expanded, 40 cases). The expectant pregnant time, adverse perinatal outcome and incidence of maternal complications were compared among the three groups.
      ResultsThe gestational week of delivery in volume expansion group(albumin group and plasma group)was longer than that in control group(P < 0.05), and the incidence of fetal growth restriction was lower than those in control group(P < 0.05). The incidence of placental abruption and postpartum hemorrhage in plasma group was lower than that in control group(P < 0.05), and the incidence of renal function injury in plasma group was lower than that in albumin group(P < 0.05).
      ConclusionsThe efficacy of volume expansion therapy with albumin and plasma in the treatment of early onset preeclampsia is significant, which can prolong gestational week and improve perinatal outcome without increasing maternal complications.

       

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