不孕女性维生素D水平与卵巢储备功能的相关性研究

徐上; 栗嘉明; 马娟

doi:10.13898/j.cnki.issn.1000-2200.2022.09.009

不孕女性维生素D水平与卵巢储备功能的相关性研究

Correlation between vitamin D level and ovarian reserve function in infertile women

摘要

摘要:
目的探讨不孕女性维生素D水平与卵巢储备功能各指标之间的相关性。
方法选取不孕女性80例，检测25(OH)D₃、抗苗勒氏管激素(AMH)、促卵泡激素(FSH)水平，超声检查观察窦卵泡计数(AFC)，分析25(OH)D₃水平与AMH、FSH、AFC各指标的相关性。
结果80例不孕女性中，维生素D缺乏26例(32.50%)，不足19例(23.75%)，充足35例(43.75%)。按照维生素D缺乏、不足和充足分组，3组年龄、体质量指数、不孕年限、不孕原因和AMH、AFC、FSH各指标差异均无统计学意义(P>0.05)。多重线性回归显示，25(OH)D₃水平与AMH、FSH、AFC指标均无明显相关关系(P>0.05)。
结论不孕女性维生素D水平与卵巢储备功能各项指标均无明显相关关系，补充维生素D可能没有改善不孕女性卵巢储备功能的作用。

Abstract:
ObjectiveTo investigate the correlation between vitamin D level and ovarian reserve function in infertile women.
MethodsEighty infertile women were selected.25(OH)D₃, anti-Müllerian hormone (AMH), follicular stimulating hormone (FSH) level were detected.Sinus follicle count (AFC) was observed by ultrasonography.The correlation between 25(OH)D₃ level and AMH, FSH, AFC was analyzed.
ResultsAmong the 80 infertile women, 26 cases(32.50%) were deficient in vitamin D, 19 cases(23.75%) were insufficient in vitamin D, and 35 cases(43.75%) were sufficient in vitamin D.There were no significant differences in age, body mass index, infertility years, infertility reasons and endocrine among the 3 groups of patients with different 25(OH)D₃ level (P>0.05).Multiple linear regression showed that 25(OH)D₃ level was not correlated with AMH, FSH, AFC(P>0.05).
ConclusionsThere was no correlation between vitamin D level and various indicators of ovarian reserve function in infertile women, and vitamin D supplementation may not improve ovarian reserve function in infertile women.

HTML全文

参考文献(18)

施引文献

资源附件(0)