双重双J管置入联合N-trap网篮对嵌顿性输尿管结石钬激光碎石术后狭窄的预防作用

    Protective effect of two double-J stents placement combined with N-trap stone basket agains postoperative ureteral stricture after ureteroscopic Ho: YAG lithotripsy

    • 摘要:
      目的探讨输尿管镜钬激光碎石术后置入2根双J管联合术中N-trap网篮对术后输尿管狭窄的预防效果。
      方法回顾性分析因嵌顿性结石行输尿管镜钬激光碎石术后留置单根F7双J管或2根F6双J管病人临床资料,按倾向性评分法,以结石长径及嵌顿时间匹配入组97对(n=194),比较2组病人术后狭窄发生率(置管8~10周,随访终点时间1年)、净石率及双J管相关尿路症状发生率。
      结果术后首日复查病人总体净石率达到88.1%(171/194),2组净石率差异无统计学意义(P>0.05);拔除双J管后随访过程中共发现输尿管狭窄22例,总发生率为11.3%,其中单根F7双J管组输尿管狭窄发生率明显高于2根F6双J管组(P < 0.01),留置2根F6双J管是输尿管镜碎石术后输尿管狭窄发生的保护因素(RR=0.294,95%CI 0.113~0.766);2组双J管相关尿路症状(发生肉眼血尿、尿急、尿频、下腹痛、腰痛中至少一项)发生率均接近100%,差异无统计学意义(P>0.05)。
      结论嵌顿性输尿管结石行输尿管镜钬激光碎石术后置入2根双J管配合术中N-trap网篮的使用能更为安全、可靠地降低术后输尿管狭窄的发生风险。

       

      Abstract:
      ObjectiveTo investigate the protective effect of two double-J stents placement combined with N-trap stone basket against postoperative ureteral stricture after ureteroscopic Ho: YAG lithotripsy.
      MethodsInformation of patients with impacted ureteral stones who underwent single F7 or two F6 double-J stents placement during ureteroscopic Ho: YAG lithotripsy was retrospectively reviewed.A total of 97 pairs of patients (n=194) were distributed into two groups (single-F7 stents group and two-F6 stents group) by means of propensity score matching with stone size and impaction period being predictors.Postoperative ureteral stricture rate (with stents in place for 8 to 10 weeks and 1 year follow-up), stone-free rate and stent-related urinary symptom incidence were compared between two groups.
      ResultsOn the first day after operation, the overall stone free rate of patients reached 88.1% (171/194), and there was no significant difference between the two groups (P>0.05).During follow-up after stent removal, 22 cases of ureteral stricture (overall incidence 11.3%) were diagnosed.The incidence of ureteral stenosis in the single-F7 stents group was significantly higher than that in the two-F6 stents group (P < 0.01).Indwelling two F6 double-J stents was a protective factor for ureteral stricture after ureteroscopic lithotripsy (RR=0.294, 95%CI: 0.113-0.766).Incidence of stent-related urinary symptoms (at least one of gross hematuria, urgency, frequent urination, lower abdominal pain, flank pain) reached almost 100% in both groups, and showed no significant difference(P>0.05).
      ConclusionsAfter ureteroscopic Ho: YAG lithotripsy for incarcerated ureteral calculi, the placement of two double-J stents combined with N-trap stone basket can safely and reliably reduce the risk of postoperative ureteral stricture.

       

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