多节段脊髓型颈椎病椎管扩大成形术疗效的自身影响因素研究

    Study on the self-influencing factors of the therapeutic effecs of expansive laminoplasty for multilevel cervical spondylotic myelopathy

    • 摘要:
      目的探讨多节段脊髓型颈椎病(CSM)后路单开门椎管扩大成形术疗效的自身影响因素。
      方法选择2016年12月至2018年12月120例多节段CSM病人为研究对象,均采用椎管扩大成形术治疗,随访1~3年,末次随访采用日本骨科协会(JOA)评分评价临床疗效,并设为由优良组与可差组。收集病人性别、年龄、病程等一般资料,计算致压物最大径、平均压迫率等影像学参数,组间通过单因素及多因素分析调查影响疗效的独立影响因素。
      结果120例病人末次随访疗效评价优34例,良61例,可20例,差5例,优良率79.17%;优良组与可差组病程、年龄、致压物最大径、平均压迫率、脊髓漂移距离、术前Cobb角、术前JOA评分差异均具有统计学意义(P < 0.05~P < 0.01);2组性别、患病节段数差异均无统计学意义(P>0.05);多因素logistic回归分析显示,病程>2年、致压物最大径>5 mm、脊髓漂移距离 < 2.6 mm、平均压迫率>30%、术前JOA评分 < 10分是影响多节段CSM椎管扩大成形术疗效的独立危险因素(P < 0.05)。
      结论椎管扩大成形术是治疗多节段CSM的有效方法,临床疗效受到病程较长、脊髓压迫程度高、术前神经功能差等自身因素的影响。

       

      Abstract:
      ObjectiveTo explore the self-influencing factors of curative effects of posterior cervical expansive single open-door laminoplasty multlevel cervical spondylotic myelopathy(CSM).
      MethodsA total of 120 patients with multlevel CSM from December 2016 to December 2018 were treated with expansive laminoplasty, and followed up for 1 to 3 years.At the last follow-up, the patients were divided into the excellent group and poor group according to the the clinical efficacy evaluated by Japanese Orthopaedic Association(JOA) score.The general data such as gender, age and disease course of patients were collected, and the maximum diameter and average compression rate of pressure objects of the image data were calculated.The independent influencing factors of the curative effects between groups were investigated using the single factor and multi-factor analysis.
      ResultsAmong 120 patients, the results of the last follow-up showed that the excellent in 34 cases, good in 61 cases, fair in 20 cases and poor in 5 cases were found, and the excellent and good rate of which was 79.17%.The differences of the disease course, age, maximum compression diameter, mean compression rate, spinal drift distance, preoperative Cobb angle and preoperative JOA score between two groups were statistically significant(P < 0.05 to P < 0.01).The differences of the sex and number of disease segments between two groups were not statistcially significant(P>0.05).The results of multivariate logistic regression analysis showed that the course of disease more than 2 years, maximum diameter of the pressure object more than 5 mm, spinal cord drift distance less than 2.6 mm, average compression rate more than 30% and preoperative JOA score less than 10 were the independent risk factor affecting the efficacy of expansive laminoplasty for multlevel CSM.
      ConclusionsThe spinal enlargement is an effective method for treating multilevel CSM.The clinical efficacy is affected by its own factors such as longer course of disease, high degree of spinal cord compression and poor neurological function before surgery.

       

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