Abstract:
ObjectiveTo investigate the intervention effect of symptom management dynamic model on oropharyngeal symptom cluster in nasopharyngeal carcinoma (NPC) patients undergoing concurrent chemo-radiotherapy.
MethodsOne hundred and four patients with NPC undergoing concurrent chemo-radiotherapy were randomly divided into intervention group (53 cases) and control group (51 cases).The control group was given routine nursing and symptom management log, while the intervention group was given symptom management dynamic model on the basis of control group.The intervention began on day 1 of radiotherapy and ended 2 weeks after discharge, a total of 8 weeks.The severity of oropharyngeal symptoms was compared between the two groups at the end of the second week, the fourth week and the sixth week after the intervention and at the end of the second week after discharge.The quality of life between the two groups was compared before and after the intervention.
ResultsThe symptom scores of pain, abnormal taste, dysphagia, sticky saliva and dry mouth showed time effects and inter-group effects both in the two groups, and positive interaction effects were found for pain and abnormal taste symptoms (P < 0.05 to P < 0.01).After intervention, The physical, cognitive and emotional domains of quality of life in the intervention group was higher than those of the control group (P < 0.05 to P < 0.01).After intervention, the quality of life of patients in social, physical, role and function domain were higher than before (P < 0.05).
ConclusionsThe symptom management dynamic model can significantly reduce the severity of oropharyngeal symptom cluster and improve the quality of life of patients with NPC with concurrent chemo-radiotherapy.