韩立民, 沈燕, 徐斌斌, 黄永斌. 两种方法治疗输尿管结石临床效果比较[J]. 蚌埠医科大学学报, 2023, 48(12): 1693-1696. DOI: 10.13898/j.cnki.issn.1000-2200.2023.12.016
    引用本文: 韩立民, 沈燕, 徐斌斌, 黄永斌. 两种方法治疗输尿管结石临床效果比较[J]. 蚌埠医科大学学报, 2023, 48(12): 1693-1696. DOI: 10.13898/j.cnki.issn.1000-2200.2023.12.016
    HAN Li-min, SHEN Yan, XU Bin-bin, HUANG Yong-bin. Comparison of clinical effects of two methods in the treatment of ureteral calculi[J]. Journal of Bengbu Medical University, 2023, 48(12): 1693-1696. DOI: 10.13898/j.cnki.issn.1000-2200.2023.12.016
    Citation: HAN Li-min, SHEN Yan, XU Bin-bin, HUANG Yong-bin. Comparison of clinical effects of two methods in the treatment of ureteral calculi[J]. Journal of Bengbu Medical University, 2023, 48(12): 1693-1696. DOI: 10.13898/j.cnki.issn.1000-2200.2023.12.016

    两种方法治疗输尿管结石临床效果比较

    Comparison of clinical effects of two methods in the treatment of ureteral calculi

    • 摘要:
      目的探讨输尿管结石应用两种方法治疗的临床效果。
      方法将184例输尿管结石病人随机分成2组,均采取B超定位冲击波碎石术。对照组91例,术后口服金钱草颗粒剂2周。观察组93例,碎石前分别口服盐酸坦洛新缓释片和呋噻米片,术后每天冲服“双金排石冲剂”和盐酸坦洛新缓释片,共2周。观察结石定位时间和完全粉碎率,术中、术后和总的结石排净率,输尿管分段结石排净率及并发症发生率。
      结果观察组结石定位时间显著低于对照组(P < 0.01)。2组碎石颗粒散开距离、碎石颗粒最大横径比较差异均有统计学意义(P < 0.05)。观察组结石完全粉碎率和术中、术后及总结石排净率均显著高于对照组(P < 0.01)。2组输尿管下段结石排净率比较差异有统计学意义(P < 0.05)。观察组病人术后尿白细胞阳性、镜下血尿、肉眼血尿、疼痛及石街发生率均低于对照组,差异有统计学意义(P < 0.05~P < 0.01)。
      结论术前应用利尿剂、α1A受体阻滞剂体外冲击波碎石,术后给予“双金排石冲剂”联合坦洛新排石,结石定位时间短,碎石效果好,结石排净率高,并发症发生率低。

       

      Abstract:
      ObjectiveTo investigate the clinical effect of two methods in the treatment of ureteral calculi.
      MethodsA total of 184 patients with ureteral calculi were randomly divided into two groups.Both groups were treated with B-ultrasound-guided shock wave lithotripsy.The control group (91 cases) was given Jinqiancao granules orally for 2 weeks after operation.The observation group (93 cases) was treated with tanluoxin hydrochloride sustained-release tablets and furosemide tablets before lithotripsy.After operation, Shuangjin Paishi granules and tanluoxin hydrochloride sustained-release tablets were taken every day for 2 weeks.The positioning time and rate of complete stone crushing, intraoperative, postoperative and total stone free rate, ureteral segmental stone free rate, and complication rate were observed.
      ResultsThe stone localization time in the observation group was significantly shorter than that in the control group (P < 0.01).The dispersion distance of crushed stone particles and the maximum transverse diameter of crushed stone particles were significantly different (P < 0.05).The rate of complete stone crushing, intraoperative, postoperative and total stone free rate in the observation group were significantly higher than those in the control group (P < 0.01).There was a statistically significant difference in the clearance rate of lower ureteral calculi between the two groups (P < 0.05).The incidences of postoperative WBC positive urine, microscopic hematuria, gross hematuria, pain and stone street in the observation group were lower than those in the control group (P < 0.05 to P < 0.01).
      ConclusionsThe extracorporeal shock wave lithotripsy, which applies diuretics and α 1A receptor blocker before operation, and Shuangjin Paishi granule combined with tanluoxin hydrochloride after operation, has the advantages of short stone localization time, good lithotripsy effect, high stone free rate and low complication rate.

       

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