ObjectiveTo explore the application value of hysteroscopic cold knife technique in patients with uterine submucosal myoma of uterus and fertility requirements.

MethodsA total of 90 patients with submucosal myoma of the uterus were selected as the study subjects, with 45 patients treated with hysteroscopic cold knife technique as the observation group and 45 patients treated with hysteroscopic electrocautery as the control group.The differences in intraoperative bleeding volume, surgical time, complications, inflammatory indicators (interleukin-6, C reactive protein) before and on the first day after surgery, intrauterine adhesions and endometrial thickness at 3 months after surgery, and pregnancy at 12 months after surgery between the two groups of patients were compared.

ResultsCompared with the control group, the observation group had shorter surgical time, lower incidence of complications, lower postoperative inflammatory indicators, good endometrial repair status and higher pregnancy rate (P < 0.05 to P < 0.01).

ConclusionsThe hysteroscopic cold knife technique has the advantages of short surgical time, fewer complications, low incidence of uterine adhesions, minimal damage to the endometrium and high postoperative pregnancy rate in the treatment of submucosal myoma of uterus in patients with fertility requirements, which is a minimally invasive surgery worthy of popularization.