Objective  To explore the application effects of nursing intervention based on chronic disease trajectory model in patients with ulcerative colitis.

Methods  A total of 86 patients with ulcerative colitis were divided into the observation group(using nursing intervention based on chronic disease trajectory model) and control group(using conventional nursing intervention) according to lottery method(43 cases in each group).The health promotion lifestyle and symptom distress were compared between two groups before and after intervention.

Results  There was no statistical significance in the differences of the symptom distress rate of general activity, work, mood, interpersonal relationship, walking and interest between two groups after intervention and on the day of discharge(P>0.05), and there was no statistical significance in the disturburance degree between two groups(P>0.05).After 4 weeks of discharge, the disturbance rate of general activity, work, mood and interest in the observaton group was higher than those in control group(P < 0.05), but the disturburance degree in the observation group was significant bettter than that in control group(P < 0.01).Before intervention, there was no statistical significance in all dimensions of health-promoting lifestyle between two groups(P>0.05).On the day of discharge and 4 weeks after discharge, the scores of all dimensions in the observation group were higher than those in control group (P < 0.05 to P < 0.01).

Conclusions  Nursing intervention based on chronic disease trajectory model is helpful to reduce the rate and degree of symptom distress, and improve the health promoting lifestyle of patients.