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    急性上消化道出血再出血的危险因素分析

    Analysis of risk factors for rebleeding in acute upper gastrointestinal bleeding

      摘要
    • 摘要:
      目的 探讨急性上消化道出血(AUGIB)病人再出血危险因素。
      方法 回顾性分析50例AUGIB病人的临床相关资料，按是否再出血分为再出血组和未再出血组，对2组病人临床资料进行分析，探讨发生再出血的危险因素。
      结果 AUGIB病人中再出血组12例(24%)、未再出血组38例(76%)，男女比例为3.5∶1，消化性溃疡30例；2组呕血、中性分叶核比例、红细胞分布宽度、血小板、白蛋白、凝血酶原时间、活化部分凝血活酶时间、凝血酶时间、纤维蛋白原、血浆D-二聚体等差异均有统计学意义(P < 0.05~P < 0.01)；logistic回归分析显示：D-Dimer(OR: 0.994，95%CI：0.989~1.000)、血小板(OR: 1.066，95%CI：0.994~1.144)是AUGIB病人发生再出血的独立危险因素。
      结论 AUGIB多见于男性，消化道性溃疡伴出血最为常见，血小板、血浆D-二聚体水平是发生再出血的独立危险因素。

       

      Abstract:
      Objective To explore the risk factors for rebleeding in patients with (AUGIB).
      Methods A retrospective analysis was conducted on the clinical data of 50 patients with AUGIB, who were divided into a rebleeding group and a non-rebleeding group based on whether they experienced rebleeding.The clinical data of the two groups of patients were analyzed to explore the risk factors for rebleeding.
      Results Among AUGIB patients, there were 12 cases (24%) in the rebleeding group and 38 cases (76%) in the non-rebleeding group, with a male to female ratio of 3.5∶1.There were 30 cases of peptic ulcer.There were statistically significant differences in vomiting blood, proportion of neutrophils, red blood cell distribution width, platelets, albumin, prothrombin time, activated partial thromboplastin time, thrombin time, fibrinogen, and plasma D-dimer between the two groups (P < 0.05 to P < 0.01).Logistic regression analysis showed that D-Dimer (OR: 0.994, 95%CI: 0.989-1.000) and platelets (OR: 1.066, 95%CI: 0.994-1.144) were independent risk factors for rebleeding in AUGIB patients.
      Conclusions AUGIB is more common in males, and gastrointestinal ulcers with bleeding are the most common.Platelet and plasma D-dimer levels are independent risk factors for rebleeding.

       

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