Objective To investigate the incidence and influencing factors of complications of midline catheter in children in neonatal intensive care unit (NICU).

Methods A total of 178 newborns with midline catheter admitted to NICU of a tertiary hospital from February 2021 to June 2022 were selected as the study subjects.According to whether catheter-related complications occurred, the children were divided into the occurrence group and the non-occurrence group, and the basic information, catheterization conditions, fixation methods and other data of the two groups were collected.Univariate analysis and binary logistic regression analysis were used to analyze the related factors of neonatal midline catheter complications.

Results Among the 178 cases, 33 cases were in the occurrence group, and the incidence of complications was 18.53%.Univariate analysis showed that birth weight, puncture vein, catheter tip location, catheter retention time and internal fixation were related to the occurrence of neonatal midline catheter complications (P < 0.05 to P < 0.01).Multivariate regression analysis showed that the selection of superficial temporal vein and cephalic vein for puncture, catheter tip location in jugular vein, and no internal fixation were independent risk factors for neonatal complications related to midline catheter (P < 0.05).

Conclusions When the midline catheter is used in neonates, the insertion of the noble vein or the median cubital vein, the distal position of the catheter tip in the subclavian vein or the axillary vein, and the fixation method of internal fixation can reduce the incidence of complications of the midline catheter in neonates.