Objective To explore the correlation between self-efficacy and self-management ability and medication compliance in patients with hepatitis B cirrhosis.

Methods A total of 110 patients with hepatitis B cirrhosis were distributed a general information survey questionnaire, the general self-efficacy scale (GSES), the exercise of self-care ayency scale (ESCA), and the Chinese version of the 8-item Morisky medication adherence scale(MMAS-8) to the research subjects.The correlation of the survey results was analyzed, and mediation effect analysis was conducted.

Results Among the 110 patients, there were 47 patients with MMAS-8 scores greater than 6 points, accounting for 42.73%.Their GSES score was (30.75±2.51) points, ESCA score was (117.99±25.91) points, and MMAS-8 score was (5.27±1.14) points.Patients with advanced self-management ability had the highest GSES and MMAS-8 scores, while patients with low self-management ability grading had the lowest GSES and MMAS-8 scores, and the differences were statistically significant (P < 0.01).The self-efficacy score of patients with hepatitis B cirrhosis was positively correlated with the self-management ability score and medication compliance score (r=0.395, 0.473, P < 0.05), and the self-management ability score was positively correlated with medication compliance score (r=0.452, P < 0.05).The self-efficacy played a part of mediating effect between the self-management ability and medication compliance of patients with hepatitis B cirrhosis, the direct effect was 4.61, the indirect effect was 0.190, and the total effect was 0.651.The mediating effect accounted for 29.18% of the total effect.

Conclusions The medication compliance of patients with hepatitis B cirrhosis is relatively low.In clinical intervention, not only the medication compliance of patients can be improved by improving their self-management ability, but also the medication compliance can be indirectly improved by improving their self-management ability and self-efficacy, providing more research ways to improve the medication compliance of patients with hepatitis B cirrhosis.