Objective To study the endoscopic, clinical features and changes of detection rate of fundic gland polyps(FGP).

Methods The clinical and endoscopic data of patients with FGP diagnosed by pathology in The Second Hospital of Jiaxing in 2001, 2011 and 2021 were collected, and divided into the 2001 group, 2011 group and 2021 group, respectively.The data were compared among three groups.At the same time, the data of patients with non-FGP(the non-FGP group)in 2021 were collected, and compared with the 2021 group.

Results The detection rates of the 2001 group, 2011 group and 2021 group were 0.53% (11/2063), 0.94% (51/5422) and 11.04% (2008/18186), respectively, and which gradually increased.The proportions of gastric polyps detected by endoscope in the 2001 group, 2011 group and 2021 group were 19.64%, 19.77% and 80.58%, respectively.The mean age of three groups showed an increasing trend(P < 0.01), and the most common sites of FGP in three groups were gastric corpus and gastric fundus.Compared with the non-FGP group, the age of patients was lower, the proportion of female was higher, the stomach body and fundus were more common, and the infection rate of Helicobacter pylori(Hp) was lower in the FGP group(P < 0.05 to P < 0.01).

Conclusions The detection rate and proportion of FGP in gastric polyps significantly increase, the FGP is more common in women, mostly locates in the stomach body and fundus, and the patients with non-Hp infection may be more susceptible to FGP.